Inspiration for 100 Year Starship came from the one-hundred year period between Jules Verne's publication of From Earth To The Moon and humankind's arriving to the moon. Using this formula, 100 Year Starship has us aiming for an interstellar trip—from earth to another star system—in 2012 in order to achieve this goal in, approximately, 2112.
Noting that the 100 year goal is a target not a dealing, and bearing in mind that in 1865 it would have been impossible to get to the moon, how are we in 2012 to prepare for a space adventure using technology or techniques we can only guess at and which are most certainly not yet invented or discovered?
Which leads to the real question: What can we do now in 2012 for the interstellar goal of 2112?